Yes, except for vaccines that target virus(es) that are part of a group in which there may be only a 15-59% chance that it will protect outside of the laboratory. Per the Lancet and per the CDC, this is the case with seasonal flu vaccines. And, you have a small percentage actually die or have ongoing health problems because of problems with the vaccine.
References:
"The Lancet medical journal, the study found the seasonal flu jab, available free to seniors, is only 59 per cent effective...": http://www.theaustralian.com.au/news/health-science/seasonal...
"Influenza vaccine would be estimated to be only 15% effective": http://www.cdc.gov/flu/professionals/vaccination/effectivene...
http://www.cdc.gov/flu/protect/keyfacts.htm#side-effects