Nginx does not support CGI, but you can for example use uWSGI as a application server behind nginx.

For reference, WSGI is python only, it's an interprocess communication method very similar to fastcgi with the same purpose.

Seems like it can work with others too, though I don't know how well: https://uwsgi-docs.readthedocs.io/en/latest/LanguagesAndPlat...

Reading that documentation page will tell you that nginx cannot spawn fastcgi processes ;)