I am currently doing it. Spent 4 weeks in Stockholm, two weeks in Cluj Romania, currently in Prague as I type this. Next up is Berlin. I am from San Francisco, and have one startup (https://commando.io) that has paying customers, and also working on a new company as well.

So far I love it. Though I will admit, it sometimes can be difficult to put in the hours when there are so many things to see, people to meet, and things to explore. Also, I am not exactly doing it like a backpacker/cheap either, which improves the experience.

Happy to answer any questions.