I was in San Diego SfN 2007, where Sebastian Seung talked about the brain as a device maximizing reward globally.
In any case, manually segmented data from my lab already went to Sebastian's lab. They are testing their convolutional networks on it--I hope they get them to work.
http://t2.ini.uzh.ch/data.html
If I have to go over several terabytes of images, manually segmenting like that, I'll need to live a thousand lives.